TOP GUIDELINES OF FENTANYL RENAL FAILURE

Monitor Closely (one)oxcarbazepine will decrease the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Coadministration of fentanyl with CYP3A4 inducers could lead on to the reduce in fentanyl plasma concentrations, lack of efficacy or, possibly, development of the withdrawal